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Kapanlagi.com - The sister of legendary singer Celine Dion, Claudette, shared the latest information about the rare disease her sister is suffering from, which is Stiff Person Syndrome.
Celine Dion is reported to no longer have control over her muscles. The disease that Celine Dion has is progressive and incurable, causing her body to attack its own nerve cells. This can have a negative impact on Celine Dion's work.
Based on Claudette's story, Celine Dion is trying to fight her illness and wants to return to the stage.
Although the disease that Celine Dion has still requires research and finding a well-functioning treatment, Celine Dion's family continues to support her and seeks a way for her recovery.
Summarized from Liputan6.com, on Friday (22/12/23), here is an explanation of Celine Dion's disease and its symptoms.
Celine Dion Portrait (Instagram/@celinedion)
Celine Dion is reported to have a rare disease called Stiff Person Syndrome (SPS), in 2022.
Stiff Person Syndrome is a rare neurological condition that causes muscle stiffness and spasms.
In addition, SPS can affect how the brain and spinal cord regulate muscle movements.
Celine Dion Portrait (Instagram/@celinedion)
Stiff Person Syndrome starts at age 30 - 60 and occurs more frequently in women.
This disease can disrupt the quality of life of sufferers, as it is a rare disease and only affects 1-2 people per one million people.
Portrait of Celine Dion (Instagram/@celinedion)
Stiff Person Syndrome is classified as an autoimmune disorder.
Most patients with SPS have antibodies against glutamic acid decarboxylase (GAD), a protein in inhibitory nerve cells that is involved in the production (synthesis) of the main inhibitory neurotransmitter called gamma-aminobutyric acid (GABA).
Portrait of Celine Dion (Instagram/@celinedion)
The role of gamma-aminobutyric acid (GABA) is to regulate muscle movement and prevent hyperexcitability in the nervous system.
However, SPS symptoms can develop when the immune system attacks certain nerve cells (neurons) that produce GAD, leading to a decrease in GABA levels in the body.
Portrait of Celine Dion (Instagram/@celinedion)
The symptoms experienced by patients with Stiff Person Syndrome (SPS) are stiff limbs, stiff muscles in the trunk, stooped posture, painful muscle spasms, difficulty walking, and sensory problems such as sensitivity to light, noise, and sound.
Other symptoms experienced by SPS patients include seizures that can cause them to fall when standing and can break bones.
Portrait of Celine Dion (Instagram/@celinedion)
In addition to stiff muscles, patients with Stiff Person Syndrome (SFS) may also experience depression or anxiety due to other symptoms they may be experiencing or a decrease in neurotransmitters in the brain.
Celine Dion married Rene Angelil, a music producer. Later, Rene Angelil passed away in 2016 due to cancer.
Celine is not only involved in the music industry, but also has various other businesses, including restaurants, investments, nightclubs, clothing brands, and other fields. Because of that, her income is estimated to reach around 800 million US dollars or equivalent to IDR 12 trillion.
On November 10, 2016, Celine remarried actor Stefan William in Uluwatu, Bali. The couple was then blessed with the arrival of a child on Monday, October 9, 2017. Lucio Otthild William, the baby boy, was born through a cesarean section.
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